"DDR2 DIMM memory modules are not backward-compatible with DDR DIMM , due to incompatible pin configurations, core voltage, and memory chip technology. DDR2 modules are designed with a different "key" in the edge connector to prevent insertion into incompatible memory sockets such as DDR motherboard. A DDR2 SDRAM DIMM will not fit into a standard SDRAM DIMM socket or a DDR DIMM socket. DDR2 modules use a 1.8V power supply, providing a big power saving over the 2.5V DDR modules."
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